October 6, 2024

Metformin May Help Manage Central Centrifugal Cicatricial Alopecia, Study Suggests

TOPLINE: Metformin significantly improved symptoms and resulted in hair regrowth in Black women with treatment-refractory central centrifugal cicatricial alopecia (CCCA), in a retrospective case series. METHODOLOGY: Researchers conducted a case series involving 12 Black women in their 30s, 40s, and 50s, with biopsy-confirmed, treatment-refractory CCCA, a chronic inflammatory hair disorder characterized by permanent hair loss, […]

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High-Dose Vitamin D Linked to Lower Disease Activity in CIS

COPENHAGEN, Denmark — High-dose oral cholecalciferol (vitamin D3) supplementation significantly reduces evidence of disease activity in patients with clinically isolated syndrome (CIS), results of a randomized, controlled trial suggest. In addition, cholecalciferol had a favorable safety profile and was well tolerated. “These data support high-dose vitamin D supplementation in early MS and make vitamin D

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