Hilton Lowe

Neuroprotection by the metabolic antioxidant alpha-lipoic acid

COVID Therapy /

The following abstract is written by: L Packer 1, H J Tritschler and K Wessel  Abstract Reactive oxygen species are thought to be involved in a number of types of acute and chronic pathologic conditions in the brain and neural tissue. The metabolic antioxidant alpha-lipoate (thioctic acid, 1, 2-dithiolane-3-pentanoic acid; 1, 2-dithiolane-3 valeric acid; and 6, 8-dithiooctanoic acid) […]

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The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19

COVID Therapy /

The following abstract is written by: Francesca Silvagno, Annamaria Vernone and Gian Piero  Department of Oncology, University of Torino, Via Santena 5 bis, 10126 Torino, Italy Abstract Abstract: The novel COVID-19 pandemic is affecting the world’s population differently: mostly in the presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal

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Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study

Disease Treatment /

The following abstract is written by Paul E Marik 1, Vikramjit Khangoora 2, Racquel Rivera 3, Michael H Hooper 2, John Catravas 4 References: PMID: 27940189 DOI: 10.1016/j.chest.2016.11.036 Abstract The global burden of sepsis is estimated as 15 to 19 million cases annually, with a mortality rate approaching 60% in low-income countries. Methods:  In this retrospective before-after clinical study, we compared the outcome and clinical

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The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections

Vitamin Studies /

The following abstract is written by H C Gorton, K Jarvis  References: PMID: 10543583    DOI 10.1016/s0161-4754(99)70005-9   Abstract An ever increasing demand to evaluate the effect of dietary supplements on specific health conditions by use of a “significant scientific” standard has prompted the publication of this study. Objective:  To study the effect of megadose Vitamin C in preventing

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Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications

Mineral Levels /

The following abstract is written by Ranasinghe, P., Pigera, S., Galappatthy, P. et al. References: Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications. DARU J Pharm Sci 23, 44 (2015). https://doi.org/10.1186/s40199-015-0127-4 Abstract Diabetes mellitus is a leading cause of morbidity and mortality worldwide. Studies have shown that Zinc has numerous beneficial effects in

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Effects of metformin, pioglitazone, and silymarin treatment on non-alcoholic Fatty liver disease: a randomized controlled pilot study

Disease Treatment /

The following abstract is written by Ali Akbar Hajiaghamohammadi 1, Amir Ziaee, Sonia Oveisi, Homa Masroor  References: PMID: 23087748     PMCID: PMC3475019    DOI: 10.5812/hepatmon.6099 Abstract Nonalcoholic fatty liver disease (NAFLD) is one of the most common reasons of enzyme increase in liver. In About 10 percent of patients with NAFLD, the disease progresses toward Non Alcoholic Steatohepatitis (NASH) and about one

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Zinc, Copper, and Magnesium and risks for all-cause, cancer, and cardiovascular mortality.

Mineral Levels /

The following piece is taken from the article ‘Serum copper to zinc ratio: Relationship with aging and health status’.  Leone, N., Courbon, D., Ducimetiere, P., Zureik, M. Abstract Background: Experimental data suggest that zinc, copper, and magnesium are involved in carcinogenesis and atherogenesis. Few longitudinal studies have related these minerals to cancer or cardiovascular disease mortality in

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Vitamin D and the importance of testing

Vitamin Studies /

Vitamin D –the importance of testing Vitamin D is essential for maintaining healthy bones and teeth. It also plays many other important roles in the body, including regulating inflammation and immune function. Vitamin D promotes intestinal calcium absorption and helps maintain adequate blood levels of calcium and phosphorus, which is necessary for healthy bone mineralization. The majority

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