Disease Treatment

Lactoferrin inhibits the growth of nasal polyp fibroblasts

This abstract is written byBeata Nadolska , Marcin Frączek, Tomasz Kręcicki, Maja Kocięba, Michał ZimeckiAffiliations expand PMID: 19388520   Abstract The aim of this study was to evaluate the effects of lactoferrin (LF) on the growth of fibroblasts derived from nasal polyps. We showed that the proliferation of fibroblasts was inhibited in a dose-dependent manner by both native and recombinant LF. The greatest inhibition of […]

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Metformin May Help Manage Central Centrifugal Cicatricial Alopecia, Study Suggests

TOPLINE: Metformin significantly improved symptoms and resulted in hair regrowth in Black women with treatment-refractory central centrifugal cicatricial alopecia (CCCA), in a retrospective case series. METHODOLOGY: Researchers conducted a case series involving 12 Black women in their 30s, 40s, and 50s, with biopsy-confirmed, treatment-refractory CCCA, a chronic inflammatory hair disorder characterized by permanent hair loss,

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High-Dose Vitamin D Linked to Lower Disease Activity in CIS

COPENHAGEN, Denmark — High-dose oral cholecalciferol (vitamin D3) supplementation significantly reduces evidence of disease activity in patients with clinically isolated syndrome (CIS), results of a randomized, controlled trial suggest. In addition, cholecalciferol had a favorable safety profile and was well tolerated. “These data support high-dose vitamin D supplementation in early MS and make vitamin D

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The impact of zinc on the molecular signaling pathways in the diabetes disease

The following abstract is written by: Keyvan Asghari, Zahra Sharg, Sina Fatehfar, Leila Chodari, Parsa Sameei. Originally published: Journal of Trace Elements in Medicine and Biology Volume 72, July 2022, 126985   Abstract Since there’s been an upsurge in people with diabetes or pre-diabetes conditions, many studies have been conducted to evaluate approaches for reducing

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Role of zinc in insulin regulation and diabetes

The following abstract is written by: Resham Raj Poudel, Yuvaraj Bhusal1, Biswaraj Tharu2, Nisha Kusum Kafle   Abstract Zinc (Zn) affects glucose metabolism through insulin regulation and has potential implication in diabetes. Zn deficiency has not been proven in diabetes; however, observations of hyperzincuria, hypozincemia, and Zn malabsorption in diabetes indicate additional requirements for Zn.

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Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study

The following abstract is written by Paul E Marik 1, Vikramjit Khangoora 2, Racquel Rivera 3, Michael H Hooper 2, John Catravas 4 References: PMID: 27940189 DOI: 10.1016/j.chest.2016.11.036 Abstract The global burden of sepsis is estimated as 15 to 19 million cases annually, with a mortality rate approaching 60% in low-income countries. Methods:  In this retrospective before-after clinical study, we compared the outcome and clinical

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Effects of metformin, pioglitazone, and silymarin treatment on non-alcoholic Fatty liver disease: a randomized controlled pilot study

The following abstract is written by Ali Akbar Hajiaghamohammadi 1, Amir Ziaee, Sonia Oveisi, Homa Masroor  References: PMID: 23087748     PMCID: PMC3475019    DOI: 10.5812/hepatmon.6099 Abstract Nonalcoholic fatty liver disease (NAFLD) is one of the most common reasons of enzyme increase in liver. In About 10 percent of patients with NAFLD, the disease progresses toward Non Alcoholic Steatohepatitis (NASH) and about one

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